There’s no sure-fire blueprint for success in standup comedy, but that doesn’t stop Maria Bamford from sharing her wisdom with “The Opener,” comedian Jim Tews in this new video. What’s Maria’s advice? Fill your inner void with comedy…and about 24 Diet Cokes.

Our good friends over at Punchline magazine, have put together the above audio clip featuring examples of how 18 different comics have “interacted” with crowd members who may have interrupted their standup sets. Check it out to hear how everyone from George Carlin, to Dane Cook, to Patton Oswalt, to Dave Attell handles the occasional heckler.